Infections of the central nervous system and beta 2 microglobulin in cerebrospinal fluid: relationship
Type 7 softball automatic radioimmunoassay counter. Beijing biochemical immunological preparation center provides island MGR1A PCs,miu miu borse, according to the instructions to operate by hand.Quality control of willow index: NSB< 5.B.From 37 to 54, the highest and lowest concentration in combination with standard curve rate difference > CV: &lt 30, group 9, group; CV: < 12 determination results using X in s representation,moncler jacken, the statistical methods used t test in all patients by lumbar puncture and cerebrospinal fluid in centrifugal extraction, taking supernatant were preserved at 4 degrees C the following time is not more than lO day.2 the results of the 2.1 control groups of cerebrospinal fluid MG levels for 0.8l& # 177; Guangxi medical 1996 February eighteenth volume first issue of 0.40mg \/ L.Bacterial meningitis group, fungal meningitis, viral meningitis group, group of group MG content in cerebrospinal fluid in the order of 5.32 soil 1.79mg \/ L,ugg australia, 2.2L + 0.39mg \/ L, 0.94mg \/ L+1.2l 1.8L soil in 0.56mg \/ L.Compared with the control group P = < 0.Ol, < 0.01.< 0.0l, < 0.05, the difference was significant (except for neurocysticercosis group.).In 2.28 patients with pyogenic meningitis, cerebrospinal fluid MG content of 5.67 soil 2.06mg \/ L, the system of antibiotic clinical symptoms improved, review of cerebrospinal fluid to the content of MG is 1.72 0.54mg \/ L soil decreased significantly (P < 0.01) 3 discuss 3.1 MG is a genus of low molecular weight proteins. Histocompatibility antigen (HLA), light chain part exists in all nucleated cell membranes, in immunocompetent cell recognition and activation may play a major role\".When the HLA degradation and cell update a MG with free form widely present in the serum, urine, cerebrospinal fluid, amniotic fluid, ascites and other body fluids, tissues and organs appear when immunological stress, inflammation, cellular degeneration and necrosis of tumor cells, abnormal metabolic conditions, can generate a lot of & MG, at the lesion site of body fluids in a MG content change.3.2 detection results suggested by different types of infection caused by central nervous system infections (bacterial, fungal, viral, carinii), the cerebrospinal fluid 2--M6 levels were significantly higher than those in control group,ugg italia, the significant difference, description of [~ -- M6 is elevated in cerebrospinal fluid can be used as a central nervous system infection and reliable diagnostic index of.According to the report, in addition to central nervous system infections, central nervous system tumors, stroke. ', traumatic brain injury, blood malignant tumor infiltration of the central nervous system \"can cause cerebrospinal fluid island MG increased to varying degrees, the cerebrospinal fluid & a MG testing cannot be used as a diagnosis of central nervous system infection by specific indexes of 3.3 bacterial meningitis cerebrospinal fluid to the content of MG group was higher than that of control group, fungal meningitis, viral meningoencephalitis and neurocysticercosis group, the ratio is 2.4 ~ 6.5 times + that cerebrospinal fluid MG increased with the extent of bacterial meningitis is more closely related, diagnosis ang in infections of the central nervous system cerebrospinal fluid MG increase may be due to inflammatory cell and lymphocyte infiltration,moncler zürich shop, stress response, the blood brain barrier damage.Bacterial meningitis disease range, a large number of neutral, lymph and monocyte dip flies, degeneration and necrosis of cerebral cysticercosis, relatively speaking, lame lesions is limited, less inflammatory reaction, so the former cerebrospinal ferry island ~ MG increased more significantly than the latter is its pathological basis.3.4 purulent meningitis treated by cerebrospinal fluid & MG content decreased obviously, the difference was significant (P < 0.01) + with Gong Weixing observation results are consistent. That cerebrospinal dimension MG detection of bacterial meningitis. Can be used as a reliable indicator of curative effect observation.